Interactions between tamiflu(oseltamivir) and Benemid (probenecid)
probenecid and oseltamivir (Minor Drug-Drug)
Use of probenecid may result in significantly decreased plasma clearance and significantly increased plasma levels of oseltamivir. Probenecid decreases the renal tubular secretion of oseltamivir. Dosage adjustments of oseltamivir are typically not required due to the large safety margin of oseltamivir.