symlin and Dicyclomine Interactions

Interactions between symlin(pramlintide) and Dicyclomine (dicyclomine)

dicyclomine and pramlintide (Moderate Drug-Drug)

GENERALLY AVOID: The use of pramlintide in combination with drugs that alter gastrointestinal motility (e.g., loperamide; anticholinergic agents) or drugs that slow the intestinal absorption of nutrients (e.g., alpha-glucosidase inhibitors) has not been studied. Because pramlintide slows gastric emptying, the potential for a pharmacodynamic interaction is possible.

MANAGEMENT: Due to its effect on gastric emptying, pramlintide therapy should not be considered for patients taking drugs that alter gastrointestinal motility or drugs that slow the intestinal absorption of nutrients.