sulfamethoxazole and Etravirine Interactions

Interactions between sulfamethoxazole and Etravirine (etravirine)

sulfamethoxazole and etravirine (Moderate Drug-Drug)

MONITOR: Coadministration with inhibitors of CYP450 2C19, 2C9, and/or 3A4 may increase the plasma concentrations of etravirine, which is a substrate of these isoenzymes.

MANAGEMENT: Because safety data regarding increased etravirine exposures are limited, caution is advised if etravirine is prescribed in combination with CYP450 2C19, 2C9, and/or 3A4 inhibitors.