spironolactone and Kaon cl 10 Interactions

Interactions between spironolactone and Kaon cl 10 (potassium chloride)

potassium chloride and spironolactone (Major Drug-Drug)

GENERALLY AVOID: The combination of potassium-sparing diuretics and potassium preparations may result in hyperkalemia. Death has been reported. These agents should not be used together unless the patient has documented hypokalemia while taking either agent alone.

MANAGEMENT: If this combination is used, patients should be monitored very closely for hyperkalemia. Patients should be given dietary counseling and advised to report any possible symptoms of hyperkalemia such as weakness, listlessness, confusion, tingling of the extremities, or feelings of heaviness in the legs to their physician.