spironolactone and Dextrose 10 and electrolyte no 48 Interactions

Interactions between spironolactone and Dextrose 10 and electrolyte no 48 (LVP solution with potassium)

spironolactone and LVP solution with potassium (Major Drug-Drug)

GENERALLY AVOID: The combination of potassium-sparing diuretics and potassium preparations may result in hyperkalemia. Death has been reported. These agents should not be used together unless the patient has documented hypokalemia while taking either agent alone.

MANAGEMENT: If this combination is used, patients should be monitored very closely for hyperkalemia. Patients should be given dietary counseling and advised to report any possible symptoms of hyperkalemia such as weakness, listlessness, confusion, tingling of the extremities, or feelings of heaviness in the legs to their physician.