Sonata Drug Interactions

Sonata (zaleplon) is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with Sonata (zaleplon).

Major Interactions
Darvon, Darvon-N, GHB, levomethadyl acetate, Orlaam, PP-Cap, propoxyphene, propoxyphene hydrochloride, propoxyphene napsylate, sodium oxybate, Xyrem

Moderate Interactions
40 Winks, Abilify, Abilify Discmelt, Accupril, acebutolol, Aceon, acetylcarbromal, Actiq, Adapin, Adgan, AHist, Akineton HCl, alcohol, alcohol, ethyl, Aldactone, Aler-Dryl, Aler-Tab, Alfenta, alfentanil, alfuzosin, alfuzosin extended release, All Day Allergy, Aller-Chlor, Allergia-C, Allerhist-1, Allermax, Alphagan, Alphagan P, alprazolam, alprazolam extended release, Altace, Altaryl, amiloride, amitriptyline, amoxapine, Amrix, amyl nitrite, Anafranil, Anergan 50, Antiflex, Antinaus 50, APO-Go, APO-Go Pen, Apokyn, apomorphine, apraclonidine ophthalmic, Apresoline, Aquachloral Supprettes, Aquacot, Aquatensen, Aquazide H, Arfonad, aripiprazole, Artane, Asendin, Astramorph PF, Atacand, Atarax, atenolol, Ativan, Avapro, Aventyl HCl, Avinza, azatadine, B-Vex, baclofen, Banaril, Banflex, Banophen, Beldin, Belix, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Child Dye Free, Benadryl Childrens Allergy Fastmelt, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Benahist-10, Benahist-50, benazepril, bendroflumethiazide, Benicar, Benoject-50, Benzacot, benzthiazide, benztropine, Betapace, Betapace AF, Betapace AF(obsolete), betaxolol, Bidhist, biperiden, bisoprolol, Blocadren, bosentan, Brevibloc, brimonidine ophthalmic, Bromaphen, bromocriptine, bromodiphenhydramine, brompheniramine, brompheniramine extended release, BroveX, BroveX CT, Budeprion SR, Budeprion XL, bumetanide, Bumex, Buprenex, buprenorphine, buPROPion, buPROPion 24 hour extended release, buPROPion extended release, Busodium, BuSpar, BuSpar Dividose, busPIRone, butabarbital, butalbital, Butisol Sodium, butorphanol, Bydramine, C.P.M., Calm-Aid, candesartan, Capoten, captopril, Carbacot, carbamazepine, carbamazepine extended release, Carbatrol, carbetapentane, carbinoxamine, carbinoxamine extended release, Carbinoxamine PD, Carboxine, Cardizem, Cardizem CD, Cardizem LA, Cardizem Monovial, Cardizem SR, Cardura, Cardura XL, Carduran, carisoprodol, Carozide, carteolol, Cartia XT, Cartrol, carvedilol, carvedilol extended release, Cascor, Catapres, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3, Celontin, Cesamet, cetirizine, Chem Mart Tramadol, Chlo-Amine, Chlor-Al Rel, Chlor-Mal, Chlor-Phen, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, chloral hydrate, chlordiazepoxide, chlorothiazide, Chlorphen, chlorphenesin, chlorpheniramine, Chlorpheniramine (Allergy), chlorpheniramine 24 hour extended release, chlorpheniramine extended release, chlorproMAZINE, chlorproMAZINE extended release, ChlorTan, chlorthalidone, chlorzoxazone, cimetidine, clemastine, clomiPRAMINE, clonazepam, clonidine, clonidine topical, Clopine, clorazepate, clorazepate extended release, clozapine, Clozapine Synthon, Clozaril, codeine, codeine phosphate, codeine sulfate, Codimal A, Cogentin, Compazine, Compazine Spansule, Compoz Nighttime Sleep Aid, Compro, Comtan, conivaptan, Contac 12 Hour Allergy, Cophene B, Cordron NR, Coreg, Coreg CR, Corgard, Corlopam, Cozaar, cyclizine, cyclobenzaprine, cyclobenzaprine extended release, Cymbalta, cyproheptadine, Dailyhist-1, Dalgan, Dantrium, Dantrium Intravenous, dantrolene, Dazidox, Dehydrated Alcohol, Demadex, Demadex I.V., Demerol HCl, Denzapine, Depacon, Depakene, Depakote, Depakote ER, Depakote Sprinkles, DepoDur, Deponit, deserpidine, desipramine, desvenlafaxine, Desyrel, Desyrel Dividose, dexbrompheniramine, dexmedetomidine, dezocine, Di-Phen, Diaqua, Diaqua-2, Diastat, Diastat AcuDial, Diastat Pediatric, diazepam, diazoxide, Dibenzyline, dihydrocodeine, Dilacor XR, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Dilatrate-SR, Dilaudid, Dilaudid-5, Dilaudid-HP, Diltia XT, diltiazem, diltiazem 24 hour extended release, diltiazem extended release, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, Dimetane, Dimetane Extentab, Dimetapp Allergy, Dimetapp Allergy Liquigel, Diovan, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, diphenhydrAMINE, diphenhydrAMINE citrate, diphenhydrAMINE tannate, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Diprivan, Diskets, Diucardin, Diurese, Diuril, Diuril Sodium, divalproex sodium, divalproex sodium extended release, Dizac, Dolophine, Doloral, Doloral Sirop, Doxadura, doxazosin, doxazosin extended release, doxepin, doxylamine, DPH, Dromadol SR, Dromadol XL, dronabinol, droperidol, duloxetine, Duraclon, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-50, Duragesic-75, Duramorph PF, Dyrenium, Dytan, Dytuss, Ed Chlor-Tan, Ed ChlorPed, Edecrin, Edecrin Sodium, Effexor, Effexor XR, Efidac-24 Chlorpheniramine, Elavil, enalapril, enalaprilat, Endep, Endocodone, Enduron, entacapone, Epitol, eplerenone, eprosartan, Equanil, Equetro, escitalopram, Esidrix, Eskalith, Eskalith-CR, esmolol, eszopiclone, ETH-Oxydose, ethacrynic acid, ethanol, ethosuximide, ethotoin, Ethyl Alcohol, etravirine, Exna, Eze D.S., Ezide, FazaClo, felbamate, Felbatol, fenoldopam, fentanyl, fentanyl topical, Fentora, Fexmid, FK506, flavoxate, Flexeril, Flexoject, Flexon, fluoxetine, fluoxetine extended release, fluphenazine, fluphenazine decanoate, fluphenazine enanthate, fluphenazine hydrochloride, fluvoxamine, fluvoxamine extended release, Fortovase, fosinopril, furosemide, gabapentin, Gabarone, Genahist, GenRx Tramadol, Geodon, guanabenz, guanadrel, guanethidine, guanfacine, Haldol, Haldol Decanoate, haloperidol, haloperidol decanoate, Harmonyl, HCTZ, Histaject, Histex CT, Histex I/E, Histex PD, Histex Pd 12, hydrALAZINE, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hydro Par, hydrochlorothiazide, hydrocodone, HydroDIURIL, hydroflumethiazide, Hydromorph Contin, hydromorphone, hydromorphone extended release, Hydrostat IR, hydrOXYzine, hydrOXYzine hydrochloride, hydrOXYzine pamoate, Hygroton, Hylorel, hypericum perforatum, Hyperstat, Hyrexin, Hytrin, Hyzine, Imdur, imipramine, imipramine pamoate, Inapsine, indapamide, Inderal, Inderal LA, Infumorph, InnoPran XL, Inspra, Intelence, Invega, Invirase, Ionsys, Iopidine, irbesartan, ISDN, Ismelin, ISMO, isocarboxazid, Isochron, Isordil, Isordil Tembids, Isordil Titradose, isosorbide dinitrate, isosorbide dinitrate extended release, isosorbide mononitrate, isosorbide mononitrate extended release, itraconazole, J-Tan, J-Tan PD, Kadian, Kemadrin, Keppra, Kerlone, Ketalar, ketamine, Ketek, Ketek Pak, Klonopin, Klonopin Wafer, labetalol, Larapam SR, Largon, Lasix, Levatol, levetiracetam, Levo-Dromoran, levocetirizine, levorphanol, LEVRIX, Lexapro, Librium, Lioresal, Lioresal Intrathecal, lisinopril, lithium, lithium carbonate, lithium carbonate extended release, lithium citrate, Lithobid, Lithonate, Lithotabs, Lo-Aqua, Lodrane 12 Hour, Lodrane 24, Lodrane XR, Loniten, Loqua, lorazepam, losartan, Lotensin, loxapine, Loxitane, Loxitane C, Loxitane IM, Lozol, Ludiomil, Luminal, Lunesta, Luvox, Luvox CR, Lyrica, M-Eslon, M-Oxy, M. O. S., Maolate, maprotiline, Marezine, Marinol, Marplan, Mavik, MB-TAB, Mebaral, Mellaril, Mellaril-S, meperidine, mephenytoin, mephobarbital, meprobamate, Meridia, Mesantoin, mesoridazine, Metahydrin, metaxalone, methadone, Methadose, methocarbamol, methsuximide, methyclothiazide, metoclopramide, metolazone, mibefradil, Micardis, Microzide, Midamor, midazolam, Mifeprex, mifepristone, Milontin, Miltown, Minipress, Minitran, minoxidil, Mio-Rel, Mirapex, mirtazapine, Mitran, Moban, moexipril, molindone, Monoket, Monopril, morphine, morphine 24 hour extended release, morphine extended release, Morphine IR, morphine liposomal, Morphine LP Epidural, morphine preservative-free, Morphine Rapi-Ject, Morphitec, MS, MS Contin, MS/S, MSIR, Mykrox, Myolin, nabilone, nadolol, nalbuphine, Naqua, Nardil, Nasahist B, Naturetin-10, Naturetin-5, Navane, ND-Stat, nefazodone, nelfinavir, Nervine, Neupro, Neurontin, Nightime Sleepaid, nilotinib, Niravam, Nitrek, Nitro TD Patch-A, Nitro-Bid, Nitro-Bid IV, Nitro-Dur, Nitro-Par, Nitro-Time, Nitrocot, Nitrodisc, Nitrogard, nitroglycerin, Nitroglyn E-R, Nitrol, Nitrol Appli-Kit, Nitrolingual, Nitrong, Nitropress, nitroprusside, Nitroquick, Nitrostat, Norflex, Norflex Injectable, Normodyne, Norpramin, nortriptyline, Noxafil, NTG, Nu-Med, Nubain, Numorphan HCl, Nytol Caplet, Nytol Maximum Strength, olanzapine, olmesartan, olopatadine nasal, OMS, Opana, Opana ER, opium, Opium Deodorized, Optimine, Oramorph SR, Orap, Oretic, Orfro, Ormazine, orphenadrine, orphenadrine extended release, Orphenate, oxazepam, oxcarbazepine, oxycodone, oxycodone extended release, OxyContin, Oxyfast, OxyIR, oxymorphone, oxymorphone extended release, P-Tann, P-Tex, Palgic, paliperidone, Palladone, Palladone SR, Pamelor, Paradione, Paraflex, Parafon Forte DSC, paramethadione, Pardryl, Paregoric, Parlodel, Parnate, paroxetine, paroxetine extended release, paroxetine mesylate, Patanase, Paxarel, Paxil, Paxil CR, PBZ, PBZ-SR, PediaTan, Pediatex, Pediatex 12, Pediox, Pediox-S, Peganone, penbutolol, Pentazine, pentazocine, Percolone, pergolide, Periactin, perindopril, Permax, Permitil, perphenazine, Pexeva, phenacemide, Phenadoz, Phenazine 50, phenelzine, Phenergan, Phenergan Fortis, phenobarbital, Phenoject-50, phenoxybenzamine, phensuximide, phentolamine, Phenurone, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, pimozide, pindolol, polythiazide, posaconazole, Posicor, pramipexole, prazosin, Precedex, pregabalin, Prialt, Prinivil, Pristiq, Pro-Med, prochlorperazine, prochlorperazine extended release, Procot, procyclidine, Proglycem, Prograf, Prolixin, Prolixin Decanoate, Prolixin Enanthate, Promacot, promazine, promethazine, Promethegan, Prop-A-Tane, propiomazine, propofol, propranolol, propranolol extended release, Prorex, protriptyline, Prozac, Prozac Weekly, Q-Dryl, Q-Dryl A/F, QDALL AR, Quenalin, quetiapine, quetiapine extended release, quinapril, ramipril, Rapamune, Rapiflux, Rauwolfemms, Rauwolfia 1X, rauwolfia serpentina, Reglan, Relaxazone, Remeron, Remeron SolTab, remifentanil, Remular, Remular-S, Renese, Repreve, Requip, ReQuip Follow on Pack, Requip Starter Kit, ReQuip Starter Pack, Rescudose, reserpine, Rezine, Ridramin, Rifadin, Rifadin IV, rifampin, Rimactane, Risperdal, Risperdal Consta, Risperdal M-Tab, risperidone, RMS, Robaxin, Robaxin-750, Rohist, ropinirole, rotigotine, Roxanol, Roxanol 100, Roxanol-T, Roxicodone, Roxicodone Intensol, RU-486, Saluron, saquinavir, saquinavir mesylate, Sarafem, Scot-Tussin Allergy Relief Formula, Sectral, Serax, Serentil, Seroquel, Seroquel XR, sertraline, Serzone, sibutramine, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Siltane, Simply Sleep, Sinequan, sirolimus, Skelaxin, Skelex, Sleep Tab II, Sleep Tabs, Sleep-ettes, Sleep-Eze-3, Sleepinal, sodium nitroprusside, sodium valproate, Solfoton, solotuss, Soma, Sominex, Sominex Maximum Strength Caplet, Somnicaps, Somnote, Sorbitrate, Sorine, sotalol, Sotalol Hydrochloride AF, Sotalol Hydrochloride AF(obsolete), Sparine, spironolactone, Sporanox, St. John's wort, Stadol, Stadol NS, Statex, Stelazine, Strifon Fort, Sublimaze, Subutex, Sufenta, sufentanil, Surmontil, tacrolimus, Tagamet, Tagamet HB, Talwin Lactate, Tanacof-XR, TanaHist-PD, Tasigna, Tasmar, Tavist, Tavist Allergy, Tavist-1, Taztia XT, Tegretol, Tegretol XR, telithromycin, telmisartan, Temaril, Tenex, Tenormin, terazosin, Terry White Chemists Tramadol, Teveten, thalidomide, Thalitone, Thalomid, Theraflu Thin Strips Multi Symptom, thioridazine, thiothixene, Thorazine, Tiazac, Ticon, Tigan, timolol, tizanidine, Tofranil, Tofranil-PM, tolcapone, torsemide, Total Allergy, Tracleer, traMADOL, traMADOL extended release, Tramahexal, Tramahexal SR, Tramake, Tramake Insts, Tramal, Tramal SR, Tramedo, Trandate, trandolapril, Tranxene SD, Tranxene T-Tab, tranylcypromine, traZODONE, Triaminic Allergy, Triaminic Thin Strips Cough & Runny Nose, triamterene, trichlormethiazide, Tridil, Tridione, trifluoperazine, triflupromazine, Trihexane, trihexyphenidyl, Trilafon, Trileptal, trimeprazine, trimethadione, trimethaphan camsylate, trimethobenzamide, trimipramine, tripelennamine, Tripohist, triprolidine, triprolidine extended release, Trux-adryl, Tusstat, Twilite, Ultiva, Ultram, Ultram ER, Uni-Tann, Unisom, Unisom Sleepgels Maximum Strength, Univasc, Uprima, Urispas, Uroxatral, V-Gan-25, V-Gan-50, Valium, valproic acid, Valrelease, valsartan, Valu-Dryl, Vanadom, Vanatrip, Vaprisol, Vasotec, VaZol, venlafaxine, venlafaxine extended release, Versed, VFEND, Viracept, Visken, Vistacon, Vistacot, Vistaject-50, Vistaril, Vistaril IM, Vistazine, Vistazine 50, Vivactil, voriconazole, Wal-finate, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Wytensin, Xanax, Xanax XR, Xyzal, XYZALL, Zamadol, Zamadol 24hr, Zamadol Melt, Zamadol SR, Zanaflex, Zaponex, Zarontin, Zaroxolyn, Zebeta, Zestril, Zetran, ziconotide, ziprasidone, Zoloft, Zonegran, zonisamide, Zyban, Zyban Advantage Pack, Zydol, Zydol SR, Zydol XL, Zymine, Zymine XR, Zyprexa, Zyprexa Zydis, Zyrtec, Zyrtec Hives

Minor Interactions
Adrenocot, Adrenocot L.A., Anturane, bexarotene, Bubbli-Pred, Cerebyx, Cortastat, Cortastat 10, Cortastat LA, Cotolone, Dalalone, Dalalone D.P., Dalalone L.A., De-Sone LA, Decadron, Decadron 5-12 Pak, Decadron Phosphate, Injectable, Decadron-LA, Decaject, Decaject L.A., Depo-Predate (obsolete), Dexacen-4, Dexacort Phosphate in Respihaler, Dexacort-LA, Dexacorten, dexamethasone, dexamethasone acetate, Dexamethasone Intensol, dexamethasone sodium phosphate, Dexasone, Dexasone LA, Dexone, Dexone LA, Dexpak Jr. Taperpak, Dexpak Taperpak, efavirenz, Flo-Pred, fosphenytoin, Hexadrol, Hexadrol Phosphate, Hydeltra-T.B.A., Hydeltrasol, Key-Pred, Key-Pred SP, Medicort, Medidex, Medidex LA, Mycobutin, Mysoline, Norvir, Norvir Soft Gelatin, Orapred, Orapred ODT, Pediapred, phenylbutazone, Pred-Ject-50, Predacort 50, Predaject-50, Predalone 50, Predate-50, Predcor, Predicort RP, Predicort-50, prednisoLONE, prednisoLONE acetate, prednisoLONE sodium phosphate, prednisoLONE tebutate, Prelone, Pri-Cortin 50, Priftin, Primethasone, primidone, Rezulin, rifabutin, rifapentine, ritonavir, Solurex, Solurex LA, sulfinpyrazone, Sustiva, Targretin, troglitazone

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