Drug interactions between Sandostatin and verapamil
Results for the following 2 drugs: |
|
|---|---|
| Sandostatin (octreotide) | |
| verapamil | |
Interactions between your selected drugs
verapamil ⇔ octreotide
Applies to:verapamil and Sandostatin (octreotide)
MONITOR: Somatostatin analogs (e.g., octreotide, lanreotide) can decrease heart rate and may potentiate the bradycardic effects of drugs like beta-blockers, calcium channel blockers, digitalis glycosides, and certain antiarrhythmic agents (e.g., class I antiarrhythmics, adenosine, amiodarone). Octreotide has commonly been associated with bradycardia (less than 50 bpm), conduction abnormalities, and arrhythmias in acromegalic patients. Occasional cases of sinus bradycardia and ventricular tachycardia have also been reported with lanreotide.
MANAGEMENT: Caution is advised if somatostatin analogs are prescribed with agents that exhibit bradycardic effects, including ophthalmic formulations of beta-blockers. Heart rate and blood pressure should be monitored.
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