Interactions between pseudoephedrine and Bromocriptine (bromocriptine)
bromocriptine and pseudoephedrine (Moderate Drug-Drug)
MONITOR: The combination of bromocriptine and pseudoephedrine has led to postpartum psychosis in one report. The mechanism may be due to synergistic effects of both drugs on the dopaminergic system. In addition, tachycardia, increased blood pressure, and seizure have been reported when other sympathomimetic drugs were given concomitantly. Although this interaction is potentially rare, and causality is not definite, the clinician should exercise caution when these two agents are coadministered.
MANAGEMENT: If these two drugs must be taken concurrently, the patient's cardiovascular and mental status should be closely monitored.
