propecia and Hytrin Interactions

Interactions between propecia(finasteride) and Hytrin (terazosin)

terazosin and finasteride (Minor Drug-Drug)

Study data (n=90) reported a statistically significant interaction between finasteride and terazosin affecting finasteride pharmacokinetics, but not those of terazosin. Treatment with terazosin (45 days) and finasteride (10 days) resulted in a finasteride Cmax and AUC(0-24) significantly greater than for finasteride alone. The clinical significance of this interaction remains to be determined. Earlier data (n=48) failed to reveal significant pharmacokinetic or pharmacodynamic alterations in either drug when administered concurrently. No special precautions are recommended at this time.