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Drug Interactions between Proben-C and Vanquish

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

probenecid aspirin

Applies to: Proben-C (colchicine / probenecid) and Vanquish (acetaminophen / aspirin / caffeine)

Talk to your doctor before using probenecid together with aspirin. Depending on the dose and how frequently aspirin is taken, it may interfere with the action of probenecid and reduce its effectiveness in treating gout or gouty arthritis. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

probenecid acetaminophen

Applies to: Proben-C (colchicine / probenecid) and Vanquish (acetaminophen / aspirin / caffeine)

Information for this minor interaction is available on the professional version.

Minor

aspirin caffeine

Applies to: Vanquish (acetaminophen / aspirin / caffeine) and Vanquish (acetaminophen / aspirin / caffeine)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Major

colchicine food

Applies to: Proben-C (colchicine / probenecid)

Drinking large amounts of grapefruit juice can increase your blood levels of colchicine to dangerous levels. You should avoid the consumption of grapefruit or grapefruit juice during treatment with colchicine. Let your doctor know if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, as these may be early symptoms of colchicine toxicity.

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Major

acetaminophen food

Applies to: Vanquish (acetaminophen / aspirin / caffeine)

Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aspirin food

Applies to: Vanquish (acetaminophen / aspirin / caffeine)

Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

caffeine food

Applies to: Vanquish (acetaminophen / aspirin / caffeine)

Information for this minor interaction is available on the professional version.

Minor

aspirin food

Applies to: Vanquish (acetaminophen / aspirin / caffeine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.