Drug interactions between Prevalite and Zetia
Results for the following 2 drugs: |
|
|---|---|
| Prevalite (cholestyramine) | |
| Zetia (ezetimibe) | |
Interactions between your selected drugs
cholestyramine ⇔ ezetimibe
Applies to: Prevalite (cholestyramine) and Zetia (ezetimibe)
ADJUST DOSING INTERVAL: In a study of 40 healthy hypercholesterolemic adults, concomitant administration of cholestyramine (4 g twice daily) decreased the mean area under the plasma concentration-time curve (AUC) of total ezetimibe by approximately 55%. The incremental LDL cholesterol reduction expected with the addition of ezetimibe to cholestyramine or other bile acid sequestrants may be diminished by this interaction. MANAGEMENT: Ezetimibe should be administered at least 2 hours before or 4 hours after the bile acid sequestrant.
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