potassium-citrate and Amiloride Interactions

Interactions between potassium-citrate(potassium citrate) and Amiloride (amiloride)

amiloride and potassium citrate (Major Drug-Drug)

GENERALLY AVOID: The combination of potassium-sparing diuretics and potassium preparations may result in hyperkalemia. Death has been reported. These agents should not be used together unless the patient has documented hypokalemia while taking either agent alone.

MANAGEMENT: If this combination is used, patients should be monitored very closely for hyperkalemia. Patients should be given dietary counseling and advised to report any possible symptoms of hyperkalemia such as weakness, listlessness, confusion, tingling of the extremities, or feelings of heaviness in the legs to their physician.