piperacillin and Arduan Interactions

Interactions between piperacillin and Arduan (pipecuronium)

piperacillin and pipecuronium (Moderate Drug-Drug)

MONITOR: Piperacillin may prolong the effects of nondepolarizing muscle relaxants. The mechanism is unknown. Data exist for vecuronium.

MANAGEMENT: Close observation for profound and prolonged respiratory depression and muscle weakness is recommended if these drugs must be used together.