penicillin and E mycin Interactions

You searched for interactions between:

• penicillin
• E mycin (erythromycin)

Interaction(s) found:

erythromycin and penicillin (Minor Drug-Drug)

Although some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are given together, neither has predictable therapeutic efficacy. Data are available for erythromycin, although theoretically this interaction could occur with any macrolide. Except for monitoring of the effectiveness of antibiotic therapy, no special precautions appear to be necessary.