pancrelipase and Alu tab Interactions

Interactions between pancrelipase and Alu tab (aluminum hydroxide)

aluminum hydroxide and pancrelipase (Moderate Drug-Drug)

ADJUST DOSING INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of some formulations of pancreatic enzymes, resulting in earlier release and destruction of enzymatic activity.

MANAGEMENT: The administration of antacids and enteric-coated pancreatic enzyme products should be separated by at least one hour.