nicorette and Alert Interactions

Interactions between nicorette(nicotine) and Alert (caffeine)

nicotine and caffeine (Minor Drug-Drug)

One study (n=12) has reported that there was a significant interactive effect of caffeine and nicotine on subjective arousal such that nicotine decreased arousal only in the presence of caffeine. The exact mechanism of this interaction has not been specified. Further research is needed to examine the subjective and physiological interactions between caffeine and nicotine.