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Drug Interactions between Nexium and Zantac

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between Nexium and Zantac. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Nexium

A total of 199 drugs are known to interact with Nexium.

Zantac

A total of 139 drugs are known to interact with Zantac.

Drug and food interactions

Moderate

esomeprazole food

Applies to: Nexium (esomeprazole)

Food may interfere with the absorption of esomeprazole. Esomeprazole should be taken at least one hour before meals and at the same time every day. When esomeprazole is given to patients receiving continuous enteral nutrition (tube feedings), the tube feeding should be interrupted for at least 1 hour before and 1 hour after the dose of esomeprazole. This will make it easier for your body to absorb the medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Minor

raNITIdine food

Applies to: Zantac (ranitidine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Acid suppressant agents

Therapeutic duplication

The recommended maximum number of medicines in the 'acid suppressant agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'acid suppressant agents' category:

  • Nexium (esomeprazole)
  • Zantac (ranitidine)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer