nascobal and Aminosalicylate sodium Interactions

Interactions between nascobal(cyanocobalamin) and Aminosalicylate sodium (aminosalicylate sodium)

cyanocobalamin and aminosalicylate sodium (Minor Drug-Drug)

Limited data suggest that aminosalicylic acid may decrease the gastrointestinal absorption of vitamin B12. This interaction is not proven but is theoretically possible due to a mild malabsorption syndrome that can occur in some patients treated with aminosalicylic acid. However, it should rarely lead to clinically significant deficiency because the body (primarily the liver) usually has a copious supply of vitamin B12 that can sustain a person for several years in the absence of adequate intake. As for the treatment of B12 deficiency-related anemia, parenteral or intranasal administration is generally the preferred route, which would bypass the potential interaction.