Drug interactions between Myfortic and Neoral
| Results for the following 2 drugs: |
|---|
| Myfortic (mycophenolic acid) |
| Neoral (cyclosporine) |
Interactions between your selected drugs
cyclosporine ↔ mycophenolic acid
Applies to:Neoral (cyclosporine) and Myfortic (mycophenolic acid)
Coadministration with cyclosporine has been shown in some studies to decrease serum levels of mycophenolic acid (MPA), and MPA levels have also increased significantly after discontinuation of cyclosporine. The mechanism and clinical significance are unknown. It may be appropriate to monitor for alterations in therapeutic effect and MPA trough levels whenever cyclosporine is added to or discontinued from the patient's immunosuppressant regimen. Mycophenolic acid has been shown to have no effect on the pharmacokinetics of cyclosporine in stable renal transplant patients.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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