Drug interactions between Miradon and Zetia
| Results for the following 2 drugs: |
|---|
| Miradon (anisindione) |
| Zetia (ezetimibe) |
Interactions between your selected drugs
anisindione ↔ ezetimibe
Applies to:Miradon (anisindione) and Zetia (ezetimibe)
In a study of 12 healthy adult males, coadministration of ezetimibe (10 mg once daily) had no significant effect on the bioavailability of warfarin or prothrombin time. Increased International Normalized Ratio (INR) has been reported during postmarketing use of ezetimibe in patients who had it added to warfarin. However, most of these patients were also on other medications, so the relationship to ezetimibe is uncertain. Ezetimibe product labeling recommends that the INR be appropriately monitored if ezetimibe is used in patients receiving warfarin. The effect of ezetimibe on other oral anticoagulants is unknown.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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