minocycline-hydrochloride and Penthrane Interactions

Interactions between minocycline-hydrochloride(minocycline) and Penthrane (methoxyflurane)

minocycline and methoxyflurane (Major Drug-Drug)

GENERALLY AVOID: Coadministration of tetracycline or oxytetracycline with methoxyflurane has enhanced renal toxicity. Fatalities have been reported. The mechanism is not known.

MANAGEMENT: This combination should be avoided if possible.