Drug Interactions

Drug interactions between metformin and Nifediac CC

Results for the following 2 drugs:

metformin
Nifediac CC (nifedipine)

Interactions between your selected drugs

nifedipine ⇔ metformin

Applies to: Nifediac CC (nifedipine) and metformin

MONITOR: Nifedipine may increase plasma concentrations of metformin by increasing the extent of absorption. Increased metformin levels may increase the risk of lactic acidosis.

MANAGEMENT: If nifedipine and metformin must be used together, cautious titration of metformin dosage is recommended. Increased metformin levels may increase the risk of lactic acidosis. Patients should be advised to monitor their blood glucose and to promptly notify their physician if they experience possible signs of lactic acidosis such as malaise, myalgia, respiratory distress, hyperventilation, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.

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