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Drug Interactions between Malarone Pediatric and Sulfatrim Pediatric

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

sulfamethoxazole atovaquone

Applies to: Sulfatrim Pediatric (sulfamethoxazole / trimethoprim) and Malarone Pediatric (atovaquone / proguanil)

Information for this minor interaction is available on the professional version.

Minor

trimethoprim atovaquone

Applies to: Sulfatrim Pediatric (sulfamethoxazole / trimethoprim) and Malarone Pediatric (atovaquone / proguanil)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

atovaquone food

Applies to: Malarone Pediatric (atovaquone / proguanil)

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.

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Moderate

sulfamethoxazole food

Applies to: Sulfatrim Pediatric (sulfamethoxazole / trimethoprim)

Ask your doctor before using sulfamethoxazole together with ethanol. Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Antipneumocystis agents

Therapeutic duplication

The recommended maximum number of medicines in the 'antipneumocystis agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antipneumocystis agents' category:

  • Malarone Pediatric (atovaquone/proguanil)
  • Sulfatrim Pediatric (sulfamethoxazole/trimethoprim)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer