Drug interactions between Luvox and Xanax
Results for the following 2 drugs: |
|
|---|---|
| Luvox (fluvoxamine) | |
| Xanax (alprazolam) | |
Interactions between your selected drugs
alprazolam ⇔ fluvoxamine
Applies to: Xanax (alprazolam) and Luvox (fluvoxamine)
MONITOR: Administration of fluvoxamine with certain benzodiazepines may increase CNS depression (e.g., sedation, ataxia). The mechanism appears to be inhibition of the CYP450 3A4 hepatic oxidative metabolism of the benzodiazepine. This interaction has been reported for alprazolam and diazepam, but may also occur with other benzodiazepines.
MANAGEMENT: The patient should be observed for increased CNS depression. Dosage adjustments may be required. Lorazepam, temazepam, and oxazepam, which are not metabolized by oxidative metabolism, may be better alternatives if a benzodiazepine is required.
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