Drug interactions between Lopressor and Tambocor
Results for the following 2 drugs: |
|
|---|---|
| Lopressor (metoprolol) | |
| Tambocor (flecainide) | |
Interactions between your selected drugs
metoprolol ⇔ flecainide
Applies to: Lopressor (metoprolol) and Tambocor (flecainide)
MONITOR: Beta-blockers and flecainide may have additive negative inotropic effects. Areas under the curve were increased for both drugs and negative inotropic effects occurred when flecainide and propranolol were given to normal subjects. A case of bradycardia, atrioventricular block and cardiac arrest has been reported after sotalol was added to flecainide; however, causality was not definitely determined.
MANAGEMENT: Careful monitoring of the patient's hemodynamic status is recommended during concomitant administration. The same precaution should be observed when beta blocker ophthalmic solutions are used, since they are systemically absorbed and can produce clinically significant systemic effects even at low or undetectable plasma levels. Patients should be advised to promptly report symptoms such as dizziness, slow or irregular heartbeats, syncope, or palpitations.
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