Drug Interactions

Drug interactions between Librium and omeprazole

Results for the following 2 drugs:

Librium (chlordiazepoxide)
omeprazole

Interactions between your selected drugs

chlordiazepoxide ⇔ omeprazole

Applies to: Librium (chlordiazepoxide) and omeprazole

MONITOR: Omeprazole may increase the pharmacologic effects and serum levels of certain benzodiazepines via hepatic enzyme inhibition. Diazepam and triazolam are the only benzodiazepines that have been specifically studied in this regard.

MANAGEMENT: Patient should be observed for increased sedation. Reduced benzodiazepine dosage may be indicated, especially in the elderly. Benzodiazepines not metabolized via oxidation (i.e., lorazepam, oxazepam, temazepam) are not expected to interact and may be considered as alternatives.

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