levothyroxine-sodium and Andryl 200 Interactions

Interactions between levothyroxine-sodium(levothyroxine) and Andryl 200 (nandrolone)

levothyroxine and nandrolone (Moderate Drug-Drug)

MONITOR: Androgens may induce reversible clinical hyperthyroidism in patients receiving thyroid hormone replacement therapy. The proposed mechanism is androgen-induced decrease in T4 binding globulin resulting in decreased serum T4, increased T3 uptake resin and free T4, and decreased TSH levels.

MANAGEMENT: Clinical and laboratory monitoring of thyroid function may be necessary, as may a 25% to 50% reduction in thyroid hormone dosage.