Drug interactions between Levothroid and Miradon
| Results for the following 2 drugs: |
|---|
| Levothroid (levothyroxine) |
| Miradon (anisindione) |
Interactions between your selected drugs
levothyroxine ↔ anisindione
Applies to:Levothroid (levothyroxine) and Miradon (anisindione)
MONITOR: Thyroid hormones increase the catabolism of the clotting factors dependent on vitamin K. The hypoprothrombinemic response to oral anticoagulants may be enhanced. No significant effects are expected when warfarin is added to a patient stabilized on thyroid replacement.
MANAGEMENT: INR or prothrombin time should be monitored closely when adding, discontinuing, or changing thyroid hormone dosage. Patients should be advised to notify their physician if they experience any signs of excessive anticoagulation, such as unusual or prolonged bleeding, bruising, vomiting, change in stool or urine color, headache, dizziness, or weakness.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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