levodopa and Alprazolam Interactions

Interactions between levodopa and Alprazolam (alprazolam)

alprazolam and levodopa (Moderate Drug-Drug)

MONITOR: Benzodiazepines may decrease the therapeutic effects of levodopa in patients with Parkinson's disease. The mechanism is unknown.

MANAGEMENT: Patients receiving this combination should be monitored for altered clinical response. The benzodiazepine should be discontinued if an interaction is suspected.