Drug interactions between Lasix and Tekturna
Results for the following 2 drugs: |
|
|---|---|
| Lasix (furosemide) | |
| Tekturna (aliskiren) | |
Interactions between your selected drugs
furosemide ⇔ aliskiren
Applies to: Lasix (furosemide) and Tekturna (aliskiren)
MONITOR: Coadministration with aliskiren may decrease the blood concentrations of furosemide. The mechanism of interaction has not been described. According to the product labeling for aliskiren, peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of furosemide were reduced by approximately 50% and 30%, respectively, during concomitant administration. Furosemide had no significant effect on the systemic exposure of aliskiren.
MANAGEMENT: The potential for diminished pharmacologic effects of furosemide should be considered during coadministration with aliskiren.
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