Drug interactions between Lasix and neomycin
| Results for the following 2 drugs: |
|---|
| Lasix (furosemide) |
| neomycin |
Interactions between your selected drugs
furosemide ↔ neomycin
Applies to:Lasix (furosemide) and neomycin
GENERALLY AVOID: Coadministration of parenteral aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- and nephrotoxicity due to additive or synergistic pharmacologic effects of these drugs. The risk may be greater with high dosages of either drug, preexisting renal insufficiency, advanced age, dehydration, or the presence of other oto- or nephrotoxic drugs. The onset of ototoxicity may be greatly delayed, and cochlear damage may initially be asymptomatic. Reversible and irreversible hearing losses have been reported.
MANAGEMENT: The use of aminoglycoside antibiotics in combination with loop diuretics should generally be avoided. Serial, vestibular, audiometric, and renal function tests should be performed before and during therapy if coadministration is necessary.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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