jolivette and Isotretinoin Interactions

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Interactions between jolivette(norethindrone) and Isotretinoin (isotretinoin)

Major Drug-Drug Interaction norethindrone and isotretinoin (Major Drug-Drug)

CONTRAINDICATED: Microdosed progesterone preparations (minipills) may be an inadequate form of contraception during isotretinoin therapy.

MANAGEMENT: Due to the potential for serious fetal malformations, the use of progestin-only contraceptives is contraindicated during isotretinoin therapy. At least two methods of effective contraception are mandatory during isotretinoin therapy and for at least 1 month after discontinuing therapy.