Drug interactions between isosorbide and Rogaine Extra Strength
Results for the following 2 drugs: |
|
|---|---|
| isosorbide | |
| Rogaine Extra Strength (minoxidil topical) | |
Interactions between your selected drugs
isosorbide ⇔ minoxidil
Applies to: isosorbide and Rogaine Extra Strength (minoxidil topical)
MONITOR: Theoretically, topical administration of minoxidil may potentiate the hypotensive effects of systemic minoxidil and other vasodilators. Although systemic absorption of topical minoxidil is generally minimal (approximately 1.6% to 3.9% of an applied dose), adverse cardiovascular effects such as edema, palpitations, blood pressure decreases, and increased pulse rate have been reported in a few patients. Increased systemic absorption may occur when topical minoxidil is used in excess of normally recommended dosages or applied to compromised skin. MANAGEMENT: Patients prescribed topical minoxidil in combination with systemic vasodilators or peripherally-acting antiadrenergic agents should be monitored for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache.
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