Irinotecan Drug Interactions
irinotecan is known to interact with the following drugs:
Click on a link below to view Drug-Drug Interactions with irinotecan.
Major Interactions
adalimumab,
Arava,
atazanavir,
Attenuvax,
BCG,
certolizumab,
Cimzia,
Clopine,
clozapine,
Clozapine Synthon,
Clozaril,
Denzapine,
Dryvax,
Enbrel,
Enbrel Prefilled Syringe,
Enbrel SureClick,
etanercept,
FazaClo,
FluMist,
Humira,
Humira Pen,
Humira Pen Crohn's Disease Starter Package,
hypericum perforatum,
infliximab,
influenza virus vaccine, live, trivalent,
ketoconazole,
leflunomide,
measles virus vaccine,
Meruvax II,
mumps virus vaccine,
Mumpsvax,
natalizumab,
Nizoral,
OPV,
Orimune,
panitumumab,
poliovirus vaccine, live, trivalent,
Quadramet,
Remicade,
Reyataz,
Rotarix,
RotaShield,
RotaTeq,
rotavirus vaccine,
rubella virus vaccine,
Sabin,
samarium sm 153 lexidronam,
smallpox vaccine,
St. John's wort,
thalidomide,
Thalomid,
TheraCys,
Tice BCG Vaccine,
TOPV,
typhoid vaccine, live,
Tysabri,
varicella virus vaccine,
Varivax,
Vectibix,
Vivotif Berna,
yellow fever vaccine,
YF-Vax,
Zaponex,
Zostavax,
zoster vaccine live
Moderate Interactions
acetaZOLAMIDE,
acetaZOLAMIDE extended release,
ActHIB,
Acthib (obsolete),
Adrenocot,
Adrenocot L.A.,
Afluria,
alatrofloxacin,
Aldactone,
alefacept,
alemtuzumab,
Allens Junior Cough,
Alophen,
Amevive,
amiloride,
aminoglutethimide,
amobarbital,
Amytal Sodium,
anakinra,
anthrax vaccine adsorbed,
Aplisol,
Aplitest,
aprepitant,
Aqua-Ban ,
Aqua-Ban with Pamabrom,
Aquacot,
Aqualax,
Aquatensen,
Aquazide H,
Arcalyst,
Avelox,
Avelox I.V.,
Azasan,
azathioprine,
Bandi S15,
bendroflumethiazide,
benzthiazide,
bexarotene,
Biothrax,
Bisa-Plex,
Bisac-Evac,
bisacodyl,
Bisco-Lax,
Bisolax,
Black Draught,
Boots Cough Syrup 3 Months Plus,
bosentan,
Bubbli-Pred,
bumetanide,
Bumex,
Busodium,
butabarbital,
butalbital,
Butisol Sodium,
Calcium Stool Softener,
Calube,
Campath,
candida albicans extract,
Candida Skin Test,
Candin,
carbamazepine,
carbamazepine extended release,
Carbatrol,
Carozide,
Carters Little Pills,
casanthranol,
cascara sagrada,
castor oil,
Castor Oil, USP,
Cephulac,
Cerebyx,
chlorothiazide,
chlorthalidone,
Chocolaxed,
Cholac,
cholera vaccine,
Chronulac,
Cinobac,
cinoxacin,
Cipro,
Cipro Cystitis Pack,
Cipro I.V.,
Cipro XR,
ciprofloxacin,
ciprofloxacin extended release,
Citra pH,
Citrate of Magnesia,
Citrate-Phos-Dex,
Citroma Cherry,
Citroma Lemon,
coccidioidin skin test,
Colace,
Colace Glycerin Suppositories,
Colace Micro-Enema,
Colax,
Concentrated Phillips Milk of Magnesia,
conivaptan,
Constilac,
Constulose,
Correctol,
Correctol Softgel Extra Gentle,
Cortastat,
Cortastat 10,
Cortastat LA,
Cotolone,
Cytadren,
Cytovene,
D-S Caps,
Dalalone,
Dalalone D.P.,
Dalalone L.A.,
Daranide,
dasatinib,
DC-240,
De-Sone LA,
Decadron,
Decadron 5-12 Pak,
Decadron Phosphate, Injectable,
Decadron-LA,
Decaject,
Decaject L.A.,
Deltasone,
Demadex,
Demadex I.V.,
Depo-Predate (obsolete),
Dexacen-4,
Dexacort Phosphate in Respihaler,
Dexacort-LA,
Dexacorten,
dexamethasone,
dexamethasone acetate,
Dexamethasone Intensol,
dexamethasone sodium phosphate,
Dexasone,
Dexasone LA,
Dexone,
Dexone LA,
DexPak 10 Day Taperpak,
DexPak 13 DayTaperpak,
Dexpak Jr. Taperpak,
Di-Phen,
Dialose,
Diamox,
Diamox Sequels,
Diaqua,
Diaqua-2,
dichlorphenamide,
Dilantin,
Dilantin Infatabs,
Dilantin Kapseals,
Dilantin-125,
Diocto,
Dioctocal,
Dioctosoftez,
Dioctyn,
Dioeze,
Dionex,
Diucardin,
Diurese,
Diuril,
Diuril Sodium,
Doc-Q-Lace,
Docu,
Docu Soft,
Docucal,
Doculase,
docusate,
docusate calcium,
docusate potassium,
docusate sodium,
Docusoft S,
DocuSol,
DOK,
DOS,
Dosaflex,
Doss-Relief,
Doxidan Tablet,
Dr Caldwell Laxative,
DSS,
Dulcogen,
Dulcolax Laxative,
Dulcolax Stool Softener,
Duphalac,
Dyrenium,
Edecrin,
Edecrin Sodium,
efalizumab,
efavirenz,
Eloxatin,
Emend,
Emend 3-Day,
Emend for Injection,
Emulsoil,
Enduron,
Enemeez Mini,
Engerix-B,
Engerix-B Pediatric,
enoxacin,
Enulose,
Epitol,
Epsom Salt,
Equalactin,
Equetro,
Esidrix,
Espotabs,
ethacrynic acid,
etravirine,
Evac-U-Gen,
Evalose,
Ex-Lax Chocolated,
Ex-Lax Gentle Nature,
Ex-Lax Maximum Relief Formula,
Ex-Lax Milk of Magnesia,
Ex-Lax Regular Strength Pills,
Ex-Lax Stool Softener,
Ex-lax Ultra,
Exna,
Ezide,
Factive,
Feen-A-Mint,
felbamate,
Felbatol,
Fiber Lax,
Fiber Laxative,
Fiberall Tablets,
FiberCon,
Fiberlax,
Fibernorm,
Fibertab,
filgrastim,
FK506,
Fleet Babylax,
Fleet Bisacodyl,
Fleet Glycerin Suppositories Adult,
Fleet Glycerin Suppositories Pediatric,
Fleet Mineral Oil Enema,
Fleet Sof-Lax,
Fletchers Castoria,
Fletchers Child Laxative Cherry,
Flo-Pred,
Floxin,
Floxin I.V.,
Fluarix,
FluLaval,
Fluogen,
Flushield,
FluShield (obsolete),
Fluvirin,
Fluvirin Preservative-Free,
Fluzone,
Fluzone PFS,
Fluzone Preservative-Free,
Fluzone Preservative-Free Pediatric,
Fluzone SV,
Fluzone WV,
fosaprepitant,
fosphenytoin,
Fulvicin P/G,
Fulvicin U/F,
furosemide,
G-CSF,
ganciclovir,
Gardasil,
gatifloxacin,
gemifloxacin,
Gen Lax,
Genasoft,
Generlac,
Gentlax,
Gentlax Tablet,
Gentle Laxative,
Gilseal Homecare Glycerol BP,
Glauctabs,
Glycerin,
Glycerin Suppositories Maximum Strength,
Glycerol,
Glycerol Adult,
Glycerol Infant,
Glycerol Pediatric,
GlycoLax,
GM-CSF,
grepafloxacin,
Grifulvin V,
Gris-PEG,
Grisactin 250,
Grisactin 500,
Grisactin Ultra,
Griseofulicin,
Griseofulvic,
griseofulvin,
griseofulvin microsize,
griseofulvin ultramicrosize,
haemophilus b conjugate (HbOC) vaccine,
haemophilus b conjugate (PRP-OMP) vaccine,
haemophilus b conjugate (PRP-T) vaccine,
haemophilus b conjugate vaccine (obsolete),
haemophilus b diphtheria conjugate vaccine,
haemophilus b Neisseria conjugate vaccine,
haemophilus b tetanus conjugate vaccine,
Havrix,
Havrix (obsolete),
Havrix Pediatric,
Havrix Pediatric (obsolete),
HCTZ,
hepatitis A adult vaccine,
hepatitis A pediatric vaccine,
hepatitis A vaccine (obsolete),
hepatitis B vaccine,
Heptalac,
Hexadrol,
Hexadrol Phosphate,
HibTITER,
Hibtiter (obsolete),
Histolyn-Cyl,
histoplasmin,
Histoplasmin Diluted,
HPV,
human papillomavirus vaccine,
Hycamtin,
Hydeltra-T.B.A.,
Hydeltrasol,
Hydro Par,
hydrochlorothiazide,
HydroDIURIL,
hydroflumethiazide,
Hygroton,
Ichthammol Glycerin,
Imovax Rabies,
Imovax Rabies (obsolete),
Imovax Rabies I.D. (obsolete),
Imuran,
indapamide,
influenza virus vaccine, inactivated,
Innerclean,
Intelence,
Ipol,
IPV,
Ismotic PB,
isosorbide,
Japanese encephalitis virus vaccine,
Je-Vax,
Kao-Tin,
Kaopectate Stool Softener,
Kasof,
Kepivance,
Ketek,
Ketek Pak,
Key-Pred,
Key-Pred SP,
Kineret,
Kondremul Plain,
Konsyl Fiber,
Kristalose,
lactulose,
lapatinib,
Lasix,
Laxative Gentle Suppositories,
Leader Mineral Oil Enema,
Leukine,
Levaquin,
Levaquin Leva-Pak,
levofloxacin,
Liqui Doss,
Liquid PedvaxHIB,
Liquid Pred,
Lo-Aqua,
lomefloxacin,
Loqua,
Lozol,
Luminal,
Lyme disease vaccine,
LYMErix,
Magic Bullet,
magnesium citrate,
magnesium hydroxide,
magnesium sulfate,
malt soup extract,
Maltsupex,
mannitol,
Maxaquin,
Mebaral,
Medicort,
Medidex,
Medidex LA,
Medilax,
Menactra,
meningococcal conjugate vaccine,
meningococcal polysaccharide vaccine,
Menomune A/C/Y/W-135,
mephobarbital,
Metahydrin,
Metastron,
methazolamide,
methyclothiazide,
Meticorten,
metolazone,
Mg hydroxide,
Mg sulfate,
mibefradil,
Microzide,
Midamor,
Milk of Magnesia,
Milkinol,
Millipred,
mineral oil,
Mineral Oil, Heavy,
Mineral Oil, Light,
MiraLax,
Mitrolan,
mixed respiratory vaccine,
Modane,
Modane Soft,
Mono-Vacc Test (O.T.),
moxifloxacin,
MSTA Mumps Skin Test Antigen,
Multitest CMI,
mumps skin test antigen,
Muri-Lube,
Mycobutin,
Mykrox,
Mysoline,
MZM,
nalidixic acid,
Naqua,
Natures Remedy,
Naturetin-10,
Naturetin-5,
Neggram,
Nembutal,
Nembutal Sodium,
Neoloid,
Neptazane,
Neulasta,
Neupogen,
nevirapine,
Nexavar,
nilotinib,
norfloxacin,
Noroxin,
Octycine-100,
Octycine-250,
ofloxacin,
Omnihib,
Orapred,
Orapred ODT,
Orasone,
Oretic,
Osmitrol,
Osmoglyn,
oxaliplatin,
oxcarbazepine,
palifermin,
pamabrom,
Pedia-Lax,
Pedia-Lax Liquid,
Pediapred,
Pedvax HIB,
pegfilgrastim,
Penetrex,
pentobarbital,
Perdiem Fiber Caplet,
Perdiem Overnight,
phenobarbital,
Phenolax,
phenolphthalein,
phenylbutazone,
Phenytek,
phenytoin,
phenytoin extended release,
Phenytoin Sodium, Prompt,
Phillips Milk of Magnesia,
Phillips Stool Softener,
plague vaccine,
pneumococcal 23-valent vaccine,
pneumococcal 23-valent vaccine (obsolete),
pneumococcal 7-valent vaccine,
Pneumovax 23,
Pneumovax 23 (obsolete),
Pnu-Imune 23 (obsolete),
poliovirus vaccine, inactivated,
Polycarb,
polycarbophil,
polyethylene glycol 3350,
polythiazide,
Posicor,
Pred-Ject-50,
Predacort 50,
Predaject-50,
Predalone 50,
Predate-50,
Predcor,
Predicort RP,
Predicort-50,
Prednicen-M,
Prednicot,
prednisoLONE,
prednisoLONE acetate,
prednisoLONE sodium phosphate,
prednisoLONE tebutate,
predniSONE,
Prelone,
Prevnar,
Pri-Cortin 50,
Priftin,
Primethasone,
primidone,
Prograf,
Prohibit,
Proquin XR,
Prulet,
Purge,
RabAvert,
RabAvert (obsolete),
Rabies Vaccine (obsolete),
rabies vaccine, human diploid cell,
rabies vaccine, purified chick embryo cell,
Rapamune,
Raptiva,
Ravin,
Raxar,
Recombivax HB,
Recombivax HB Adult,
Recombivax HB Dialysis Formulation,
Recombivax HB Pediatric/Adolescent,
Regulax SS,
Renese,
Resectisol,
Rezulin,
rifabutin,
Rifadin,
Rifadin IV,
rifampin,
rifapentine,
rilonacept,
Rimactane,
Saluron,
Sani-Supp,
sargramostim,
Sclavo Test-PPD,
secobarbital,
Seconal Sodium,
Senexon,
Senna,
Senna Concentrate,
Senna Lax,
Senna Smooth,
Senna-gen,
Sennalax,
Senokot,
Senokot Child,
Senokot Direct Relief,
Senokot Extra,
SenokotXTRA,
Senolax,
SenoSol,
SenoSol-X,
Silace,
sirolimus,
skin test antigens, multiple,
sodium biphosphate,
sodium citrate,
sodium phosphate,
sodium phosphate p32,
Solfoton,
Solurex,
Solurex LA,
sorafenib,
sparfloxacin,
Spherulin,
spironolactone,
SPL,
Sprycel,
Staphage Lysate (SPL),
Sterapred,
Sterapred DS,
strontium-89 chloride,
Sulfalax Calcium,
Sulfamag,
Sulfolax,
Sur-Q-Lax,
Surfak Stool Softener,
Sustiva,
tacrolimus,
Targretin,
Tasigna,
Tegretol,
Tegretol XR,
telithromycin,
Tequin,
Tequin Teqpaq,
Tetanus Toxoid,
Tetanus Toxoid Adsorbed,
Tetanus Toxoid For Booster Use Only,
Thalitone,
Therevac-SB,
Tixylix Baby,
topotecan,
torsemide,
Tracleer,
triamterene,
trichlormethiazide,
Trichophyton Allergenic Extracts,
trichophyton skin test,
Tricitrasol,
Trileptal,
troglitazone,
trovafloxacin,
Trovan,
tuberculin purified protein derivative,
Tuberculin Tine Test,
Tubersol,
Tykerb,
Typhim VI,
typhoid vaccine, inactivated,
Uni-Cenna,
Valcyte,
valganciclovir,
Vaprisol,
Vaqta,
Vaqta (obsolete),
Vaqta Pediatric,
Vaqta Pediatric (obsolete),
Veracolate,
Viramune,
X-Prep,
Zagam,
Zagam Respipac,
Zaroxolyn
Minor Interactions
Anectine,
Anectine Flo-Pack,
Arduan,
armodafinil,
atracurium,
Celexa,
cisatracurium,
citalopram,
Compazine,
Compazine Spansule,
Compro,
delavirdine,
doxacurium,
metocurine,
Metubine Iodide,
Mivacron,
mivacurium,
modafinil,
Nimbex,
Norcuron,
Nuromax,
Nuvigil,
pancuronium,
Pavulon,
pipecuronium,
prochlorperazine,
prochlorperazine extended release,
Procot,
Provigil,
Quelicin Chloride,
rapacuronium,
Raplon,
Rescriptor,
rocuronium,
succinylcholine,
Succinylcholine Chloride,
Tracrium,
tubocurarine,
vecuronium,
Vecuronium Bromide,
Zemuron
