ipecac and Active carbon Interactions

Interactions between ipecac and Active carbon (charcoal)

charcoal and ipecac (Moderate Drug-Drug)

GENERALLY AVOID: Administration of activated charcoal with ipecac may decrease the effectiveness of the ipecac. The alkaloids of ipecac may be absorbed onto the charcoal. The concomitant use of ipecac and charcoal does not appear to improve patient outcome over charcoal alone.

MANAGEMENT: Ipecac and activated charcoal are generally not administered together routinely; although the prior administration of one agent should not be considered a contraindication to the administration of the other agent if it is deemed necessary by the attending physician. If both agents are used to treat a patient, the ipecac is generally given first and the charcoal is given after vomiting has stopped.