Drug interactions between Garlic Oil and hydrochlorothiazide/olmesartan
| Results for the following 2 drugs: |
|---|
| Garlic Oil (garlic) |
| hydrochlorothiazide/olmesartan |
Interactions between your selected drugs
hydrochlorothiazide ↔ garlic
Applies to:hydrochlorothiazide/olmesartan and Garlic Oil (garlic)
Garlic has been found in some studies to lower blood pressure and may theoretically potentiate the effects of hypotensive agents. A meta-analysis of 11 randomized, placebo-controlled studies showed a mean decrease of 4.6 mmHg for systolic blood pressure and no significant effect for diastolic blood pressure in subjects treated with garlic (most often garlic powder 600 to 900 mg/day, providing 3.6 to 5.4 mg of the active component allicin) compared to placebo. In the subgroup analysis of studies where subjects had a mean baseline blood pressure in the hypertensive range (SBP 140 mmHg or higher; DBP 90 mmHg or higher), mean decrease associated with garlic was 8.4 mmHg and 7.3 mmHg, respectively, for systolic and diastolic blood pressure. There have been no reports of clinical hypotension associated with concomitant use of garlic and antihypertensive agents.
garlic ↔ olmesartan
Applies to:Garlic Oil (garlic) and hydrochlorothiazide/olmesartan
Garlic has been found in some studies to lower blood pressure and may theoretically potentiate the effects of hypotensive agents. A meta-analysis of 11 randomized, placebo-controlled studies showed a mean decrease of 4.6 mmHg for systolic blood pressure and no significant effect for diastolic blood pressure in subjects treated with garlic (most often garlic powder 600 to 900 mg/day, providing 3.6 to 5.4 mg of the active component allicin) compared to placebo. In the subgroup analysis of studies where subjects had a mean baseline blood pressure in the hypertensive range (SBP 140 mmHg or higher; DBP 90 mmHg or higher), mean decrease associated with garlic was 8.4 mmHg and 7.3 mmHg, respectively, for systolic and diastolic blood pressure. There have been no reports of clinical hypotension associated with concomitant use of garlic and antihypertensive agents.
See also...
- Hydrochlorothiazide/olmesartan Drug Interactions
- hydrochlorothiazide and olmesartan General Consumer Information
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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