ganite and Amphotericin b Interactions

Interactions between ganite(gallium nitrate) and Amphotericin b (amphotericin B)

amphotericin B and gallium nitrate (Major Drug-Drug)

CONTRAINDICATED: Concomitant use of gallium nitrate and amphotericin B may increase the risk that severe renal insufficiency will develop in patients with hypercalcemia of malignancy.

MANAGEMENT: Adequate hydration and close monitoring of renal function are recommended. The manufacturer recommends discontinuing gallium nitrate before starting therapy with other nephrotoxic agents.