famotidine and Aleve Interactions

Interactions between famotidine and Aleve (naproxen)

naproxen and famotidine (Moderate Drug-Drug)

GENERALLY AVOID: The concomitant administration of H2 blockers may increase the dissolution rate of enteric-coated naproxen, causing the drug to be released in the stomach instead of the small intestine.

MANAGEMENT: H2 antagonists should be avoided in patients taking enteric-coated formulations of naproxen.