exubera and Aloe vera Interactions

Interactions between exubera(insulin inhalation, rapid acting) and Aloe vera (aloe vera)

insulin inhalation, rapid acting and aloe vera (Moderate Drug-Drug)

MONITOR: Concomitant use of oral products containing aloe vera gel may potentiate the hypoglycemic effect of insulin and oral antidiabetic agents. Aloe vera has demonstrated hypoglycemic effects in streptozotocin-induced diabetes in rats, and limited data in diabetic patients have indicated efficacy in reducing blood glucose when used alone or in combination with oral hypoglycemic agents.

MANAGEMENT: Until further data are available, caution is advised when aloe vera is administered orally to patients receiving insulin and/or oral antidiabetic agents due to the potential for additive risk of hypoglycemia. Patients should be monitored for changes in diabetic medication requirements.