Duraphen-dm Drug Interactions

Duraphen-dm is a multi-ingredient drug consisting of:

• dextromethorphan
• phenylephrine
• guaifenesin

Interactions with each of its ingredients have been shown below:

dextromethorphan is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with dextromethorphan.

Major Interactions
Atapryl, Azilect, Carbex, Celexa, citalopram, Cymbalta, desvenlafaxine, Desyrel, Desyrel Dividose, dexfenfluramine, duloxetine, Effexor, Effexor XR, Eldepryl, Emsam, escitalopram, fenfluramine, fluoxetine, fluoxetine extended release, fluvoxamine, fluvoxamine extended release, furazolidone, Furoxone, isocarboxazid, Jumex, Lexapro, Luvox, Luvox CR, Marplan, Matulane, Meridia, Nardil, nefazodone, Parnate, paroxetine, paroxetine extended release, paroxetine mesylate, Paxil, Paxil CR, Pexeva, phenelzine, Pondimin, Pristiq, procarbazine, Prozac, Prozac Weekly, Rapiflux, rasagiline, Redux, Sarafem, selegiline, Selfemra, Selgene, sertraline, Serzone, sibutramine, tranylcypromine, traZODONE, venlafaxine, venlafaxine extended release, Zelapar, Zoloft

Moderate Interactions
Budeprion SR, Budeprion XL, buPROPion, buPROPion 24 hour extended release, buPROPion extended release, Cardioquin, Celebrex, celecoxib, cinacalcet, darifenacin, Enablex, Gleevec, imatinib, Lamisil, mibefradil, nilotinib, Norvir, Norvir Soft Gelatin, Posicor, Quin-G, Quin-Release, Quinaglute Dura-Tabs, Quinidex Extentabs, quinidine, quinidine extended release, Quinora, Ranexa, ranolazine, Rezulin, ritonavir, Sensipar, Tasigna, terbinafine, troglitazone, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Zyban Advantage Pack

Minor Interactions
amiodarone, Bextra, Cordarone, Cordarone I.V., linezolid, memantine, Namenda, Pacerone, valdecoxib, Zyvox

phenylephrine is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with phenylephrine.

Major Interactions
Adapin, amitriptyline, amoxapine, Anafranil, Asendin, Atapryl, Aventyl HCl, Azilect, Carbex, clomiPRAMINE, desipramine, doxepin, Elavil, Eldepryl, Emsam, Endep, furazolidone, Furoxone, imipramine, imipramine pamoate, isocarboxazid, Jumex, Marplan, Matulane, Nardil, Norpramin, nortriptyline, Pamelor, Parnate, phenelzine, procarbazine, protriptyline, rasagiline, selegiline, Selgene, Sinequan, Surmontil, Tofranil, Tofranil-PM, tranylcypromine, trimipramine, Vanatrip, Vivactil, Zelapar

Moderate Interactions
acarbose, acetoHEXAMIDE, Acutrim 16 Hour, Acutrim II, Maximum Strength, Acutrim Late Day, Adipex-P, Adipost, Akbeta, Aldomet, Amaryl, amphetamine, Anorex-SR, Apidra, Apidra OptiClik Cartridge, Appecon, apraclonidine ophthalmic, atomoxetine, benzphetamine, Betagan, Betagan C-Cap, Betapace, Betapace AF, Betapace AF(obsolete), Betimol, Blocadren, Bontril PDM, Bontril Slow Release, carbon dioxide, carteolol, carteolol ophthalmic, Cartrol, carvedilol, carvedilol extended release, chlorproPAMIDE, Concerta, Control, Coreg, Coreg CR, Corgard, D.H.E. 45, Daytrana, deserpidine, Desoxyn, Desoxyn Gradumet, Dexatrim, Dexatrim Caffeine Free, Dexedrine, Dexedrine Spansule, dexmethylphenidate, dexmethylphenidate extended release, dextroamphetamine, dextroamphetamine extended release, Dextrostat, DiaBeta, Diabinese, Didrex, diethylpropion, diethylpropion extended release, dihydroergotamine, Dopram, doxapram, Dymelor, Empro, ephedra, epoprostenol, ergoloid mesylates, Ergomar, ergonovine, ergotamine, Ergotrate Maleate, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Fastin, Flolan, Focalin, Focalin XR, Fortamet, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, glyBURIDE, glyBURIDE micronized, Glynase PresTab, Glyset, guanadrel, guanethidine, Harmonyl, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, Hydergine, Hydergine LC, Hylorel, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, iloprost, Inderal, Inderal LA, InnoPran XL, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Inversine, Ionamin, Iopidine, Ismelin, Istalol, Januvia, labetalol, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, Lente insulin, Levatol, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, Levobunolol, levobunolol ophthalmic, linezolid, lisdexamfetamine, ma huang, Mazanor, mazindol, mecamylamine, Mega-Trim, Melfiat, Meridia, Metadate CD, Metadate ER, metformin, metformin extended release, methamphetamine, methamphetamine extended release, Methergine, methyldopa, methylergonovine, Methylin, Methylin ER, methylphenidate, methylphenidate 24 hour extended release, methylphenidate extended release, methysergide maleate, metipranolol ophthalmic, Micronase, midodrine, miglitol, Migranal, nadolol, nateglinide, Normodyne, Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, Obephen, Obezine, Oby-Cap, Oby-Trim, Ocupress, OptiPranolol, Orinase, Orvaten, oxytocin, Panshape M, penbutolol, Phendiet, Phendiet-105, phendimetrazine, phendimetrazine extended release, Phentercot, phentermine, phentermine hydrochloride, phentermine hydrochloride extended release, phentermine resin extended release, Phentride, Phenyldrine, phenylpropanolamine, pindolol, Pitocin, Plegine, Prandin, Precose, Prelu-2, Pro-Fast HS, Pro-Fast SA, Pro-Fast SR, ProAmatine, Propagest, Propan, propranolol, propranolol extended release, prostacyclin, protamine zinc insulin, Rauwolfemms, Rauwolfia 1X, rauwolfia serpentina, regular insulin, ReliOn/Novolin N, ReliOn/Novolin R, Remodulin, repaglinide, reserpine, Rhindecon, Riomet, Ritalin, Ritalin LA, Ritalin-SR, Sanorex, Sansert, sibutramine, sitagliptin, Sorine, sotalol, Sotalol Hydrochloride AF, Sotalol Hydrochloride AF(obsolete), Starlix, Statobex, Strattera, Syntocinon, T-Diet, Tenuate, Tenuate Dospan, Teramine, Teramine ER, timolol, timolol hemihydrate ophthalmic, timolol ophthalmic, timolol ophthalmic long-acting, Timoptic Ocudose, Timoptic Ocumeter, Timoptic Ocumeter Plus, Timoptic-XE, Tol-Tab, TOLAZamide, TOLBUTamide, Tolinase, Trandate, treprostinil, Ultralente insulin, Velosulin BR, Ventavis, Visken, Vyvanse, Westrim, Westrim LA, Zantryl, Zyvox

Minor Interactions
colchicine, Eskalith, Eskalith-CR, lithium, lithium carbonate, lithium carbonate extended release, lithium citrate, Lithobid, Lithonate, Lithotabs

guaifenesin is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with guaifenesin.

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