Duogesic Drug Interactions

Duogesic is a multi-ingredient drug consisting of:

• acetaminophen
• phenyltoloxamine

Interactions with each of its ingredients have been shown below:

acetaminophen is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with acetaminophen.

Major Interactions
alcohol, alcohol, ethyl, Dehydrated Alcohol, ethanol, Ethyl Alcohol

Moderate Interactions
Actidose-Aqua, Actidose-Aqua Advance, Activated Charcoal, Activated Charcoal with Sorbitol (obsolete), Active Carbon, amobarbital, Amytal Sodium, Anturane, Arava, Avonex, Avonex Prefilled Syringe, Betaseron, Brevital Sodium, Busodium, busulfan, Busulfex, butabarbital, butalbital, Butisol Sodium, carbamazepine, carbamazepine extended release, Carbatrol, Carbomix, Carbosorb X, Cerebyx, Char-Flo with Sorbitol (obsolete), Charcoaid, Charcoaid 2000, Charcoaid-G, charcoal, Charcoal Plus DS, Charcocaps, Charcodote, Charcodote (obsolete), Charcotabs, Charcotrace, Chem Mart Nasal Decongestant Capsule, clofarabine, Clolar, Di-Phen, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, echinacea, Epitol, Equetro, ethotoin, Eucarbon, EZChar, Folex PFS, fosphenytoin, Healthstream Activated Charcoal, INH, Insta-Char, interferon beta-1a, interferon beta-1b, isoniazid, J.L. Bragg's Medicinal Charcoal, Karbons, leflunomide, Liqui-Char, Liqui-Char with Sorbitol (obsolete), Luminal, Mebaral, Medicoal, mephenytoin, mephobarbital, Mesantoin, methohexital, methotrexate, Methotrexate Sodium, Preservative Free, Myleran, Mysoline, naltrexone, Nembutal, Nembutal Sodium, Norit, Nydrazid, Optimum Charcoal, Peganone, pentobarbital, Pentothal, Pharmacia Carbosorb, phenobarbital, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, primidone, Ranexa, ranolazine, Rebif, ReVia, Rheumatrex Dose Pack, secobarbital, Seconal Sodium, Solfoton, sulfinpyrazone, Tegretol, Tegretol XR, thioguanine, thiopental, Trexall, Vivitrol

Minor Interactions
A-Spas S/L, Akineton HCl, Anaspaz, anisindione, Artane, Atreza, AtroPen, atropine, AZT, belladonna, Belladonna Tincture, Benemid, Bentyl, benztropine, biperiden, Cantil, cholestyramine, Cholestyramine Light, cimetidine, clidinium, Cogentin, Corlopam, Coumadin, Cystospaz, Cystospaz-M, darifenacin, Detrol, Detrol LA, dicumarol, Dicyclocot, dicyclomine, diflunisal, Ditropan, Ditropan XL, Dolobid, Donnamar, Enablex, Estinyl, ethinyl estradiol, fenoldopam, flavoxate, glycopyrrolate, homatropine, HyoMax FT, HyoMax SL, HyoMax SR, hyoscyamine, hyoscyamine extended release, Hyosol, Hyospaz, Hyosyne, IB-Stat, Inderal, Inderal LA, InnoPran XL, Jantoven, Kemadrin, L-hyoscyamine, Levbid, Levsin, Levsin SL, Levsinex SR, Maldemar, mepenzolate, mestranol, methscopolamine, Miradon, Nulev, oxazepam, oxybutynin, oxybutynin extended release, Oxytrol, Pamine, Pamine Forte, Prevalite, Pro-Banthine, probenecid, procyclidine, propantheline, propranolol, propranolol extended release, Quarzan, Questran, Questran Light, ranitidine, ranitidine bismuth citrate, Regurin, Retrovir, Rifadin, Rifadin IV, rifampin, Rimactane, Robinul, Robinul Forte, Sal-Tropine, Sanctura, Sanctura XR, Scopace, scopolamine, scopolamine topical, Serax, sodium salicylate, solifenacin, Spasdel, Symax Duotab, Symax FasTab, Symax SL, Symax SR, Tagamet, Tagamet HB, tolterodine, tolterodine extended release, Transderm-Scop, Trihexane, trihexyphenidyl, Tritec, trospium, trospium extended release, Urispas, Urotrol, VESIcare, warfarin, Zantac, Zantac 150, Zantac 300, Zantac 300 GELdose, Zantac 75, Zantac EFFERdose, Zantac GELdose, zidovudine

phenyltoloxamine is known to interact with the following drugs:

Click on a link below to view Drug-Drug Interactions with phenyltoloxamine.

Major Interactions
Cena K, Darvon, Darvon-N, Ed K+10, GHB, Glu-K, K + Potassium, K-10, K-8, K-Dur 10, K-Dur 20, K-Lor, K-Norm, K-Sol, K-Tab, K-Vescent (Potassium Chloride), Kaochlor, Kaochlor S-F, Kaon-CI, Kaon-CL 10, Kaon-CL 20%, Kato, Kay Ciel, KCl, KCl-20, Klor-Con, Klor-Con 10, Klor-Con 8, Klor-Con M10, Klor-Con M15, Klor-Con M20, Klor-Con/25, Klotrix, Micro-K, Micro-K 10, PC-10, potassium chloride, potassium chloride extended release, potassium citrate, PP-Cap, propoxyphene, propoxyphene hydrochloride, propoxyphene napsylate, Rum-K, Slow-K, sodium oxybate, Ten-K, Topamax, Topamax Sprinkle, topiramate, Twin-K, Urocit-K, Xyrem, Zonegran, zonisamide

Moderate Interactions
40 Winks, A-Spas S/L, Abilify, Abilify Discmelt, acetylcarbromal, acetylcholine ophthalmic, acrivastine, Actiq, Adapin, Adgan, Adsorbocarpine, AHist, Akarpine, Akineton HCl, alcohol, alcohol, ethyl, Aler-Dryl, Aler-Tab, Alfenta, alfentanil, All Day Allergy, Aller-Chlor, Allergia-C, Allerhist-1, Allermax, Alphagan, Alphagan P, alprazolam, alprazolam extended release, Altaryl, amantadine, Ambien, Ambien CR, amitriptyline, amobarbital, amoxapine, Amrix, Amytal Sodium, Anafranil, Anaspaz, Anergan 50, Antiflex, Antilirium, Antinaus 50, Antivert, Aplisol, Aplitest, APO-Go, APO-Go Pen, Apokyn, apomorphine, apraclonidine ophthalmic, Aquachloral Supprettes, ARI Sodium Iodide (I123) 1-12 MBq, ARI Sodium Iodide (I123) 100-750 MBq, Aricept, Aricept ODT, aripiprazole, Artane, Asendin, Astramorph PF, Atarax, Ativan, Atreza, AtroPen, atropine, Aventyl HCl, Avinza, azatadine, B-Vex, baclofen, Banaril, Banflex, Banophen, Beldin, Belix, belladonna, Belladonna Tincture, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Child Dye Free, Benadryl Childrens Allergy Fastmelt, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Benahist-10, Benahist-50, Benoject-50, Bentyl, Benzacot, benztropine, Bidhist, biperiden, Bonine, brimonidine ophthalmic, Bromaphen, bromocriptine, bromodiphenhydramine, brompheniramine, brompheniramine extended release, BroveX, BroveX CT, Buprenex, buprenorphine, Busodium, BuSpar, BuSpar Dividose, busPIRone, butabarbital, butalbital, Butisol Sodium, butorphanol, butorphanol nasal, Bydramine, C.P.M., Calm-Aid, candida albicans extract, Candida Skin Test, Candin, Cantil, carbachol ophthalmic, Carbacot, carbamazepine, carbamazepine extended release, Carbatrol, carbetapentane, carbinoxamine, carbinoxamine extended release, Carbinoxamine PD, Carboptic, Carboxine, Cardioquin, carisoprodol, Catapres, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3, Celontin, Cesamet, cetirizine, Chlo-Amine, Chlor-Al Rel, Chlor-Mal, Chlor-Phen, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, chloral hydrate, chlordiazepoxide, chlormezanone, Chlorphen, chlorphenesin, chlorpheniramine, Chlorpheniramine (Allergy), chlorpheniramine 24 hour extended release, chlorpheniramine extended release, chlorproMAZINE, chlorproMAZINE extended release, ChlorTan, chlorzoxazone, clemastine, clidinium, clomiPRAMINE, clonazepam, clonidine, clonidine topical, Clopine, clorazepate, clorazepate extended release, clozapine, Clozapine Synthon, Clozaril, coccidioidin skin test, codeine, codeine phosphate, codeine sulfate, Codimal A, Cogentin, Cognex, Compazine, Compazine Spansule, Compoz Nighttime Sleep Aid, Compro, Contac 12 Hour Allergy, Cophene B, Cordron NR, cyclizine, cyclobenzaprine, cyclobenzaprine extended release, Cymbalta, cyproheptadine, Cystospaz, Cystospaz-M, D-Vert, Dailyhist-1, Dalgan, Dalmane, Dantrium, Dantrium Intravenous, dantrolene, darifenacin, Dazidox, Dehydrated Alcohol, demecarium bromide ophthalmic, Demerol HCl, Denzapine, Depacon, Depakene, DepoDur, desipramine, desvenlafaxine, Desyrel, Desyrel Dividose, Detrol, Detrol LA, dexbrompheniramine, dexchlorpheniramine, dexchlorpheniramine extended release, dezocine, Di-Phen, Diamode, Diar-Aid, Diastat, Diastat AcuDial, Diastat Pediatric, diazepam, Dicyclocot, dicyclomine, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Dilaudid, Dilaudid-5, Dilaudid-HP, dimenhyDRINATE, Dimetane, Dimetane Extentab, Dimetapp Allergy, Dimetapp Allergy Liquigel, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, diphenhydrAMINE, diphenhydrAMINE citrate, diphenhydrAMINE tannate, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Diprivan, Diskets, disopyramide, disopyramide extended release, Ditropan, Ditropan XL, Dizac, DMH, Dolophine, Doloral, Doloral Sirop, donepezil, Donnamar, Doral, doxepin, doxepin topical, doxylamine, DPH, Dramamine, Dramamine II, Dramoject, Driminate, Driminate II, dronabinol, droperidol, duloxetine, Duraclon, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-50, Duragesic-75, Duramorph PF, Dymenate, Dytan, Dytuss, echothiophate iodide ophthalmic, Ed Chlor-Tan, Ed ChlorPed, Efidac-24 Chlorpheniramine, Elavil, ENA 713, Enablex, Endep, Endocodone, Epitol, Equanil, Equetro, escitalopram, Eserine Sulfate Ophthalmic, Eskalith, Eskalith-CR, estazolam, eszopiclone, ETH-Oxydose, ethanol, ethosuximide, ethotoin, Ethyl Alcohol, Exelon, Eze D.S., FazaClo, fentanyl, fentanyl topical, Fentora, Fexmid, flavoxate, Flexeril, Flexoject, Flexon, fluoxetine, fluoxetine extended release, fluphenazine, fluphenazine decanoate, fluphenazine enanthate, fluphenazine hydrochloride, flurazepam, galantamine, galantamine extended release, Genahist, Geodon, glycopyrrolate, halazepam, Halcion, Haldol, Haldol Decanoate, haloperidol, haloperidol decanoate, Histaject, histamine phosphate, Histatrol, Histex CT, Histex I/E, Histex PD, Histex Pd 12, Histolyn-Cyl, histoplasmin, Histoplasmin Diluted, homatropine, Humorsol Ocumeter, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hydrate, hydrocodone, Hydromorph Contin, hydromorphone, hydromorphone extended release, Hydrostat IR, hydrOXYzine, hydrOXYzine hydrochloride, hydrOXYzine pamoate, HyoMax FT, HyoMax SL, HyoMax SR, hyoscyamine, hyoscyamine extended release, Hyosol, Hyospaz, Hyosyne, Hyrexin, Hyzine, IB-Stat, imipramine, imipramine pamoate, Imodium, Imodium A-D, Imodium A-D EZ Chews, Imodium A-D New Formula, Imotil, Inapsine, Infumorph, Invega, Iodotope, Ionsys, Iopidine, isocarboxazid, isoflurophate ophthalmic, Isopto Carbachol, Isopto Carpine, J-Tan, J-Tan PD, Kadian, Kao-Paverin, Kaopectate Caplet, Kemadrin, Ketalar, ketamine, Klonopin, Klonopin Wafer, L-hyoscyamine, Largon, Levbid, Levo-Dromoran, levocetirizine, Levoprome, levorphanol, LEVRIX, Levsin, Levsin SL, Levsinex SR, Lexapro, Librium, Lioresal, Lioresal Intrathecal, lithium, lithium carbonate, lithium carbonate extended release, lithium citrate, Lithobid, Lithonate, Lithotabs, Lodrane 12 Hour, Lodrane 24, Lodrane XR, loperamide, lorazepam, loxapine, Loxitane, Loxitane C, Loxitane IM, Ludiomil, Luminal, Lunesta, Lyrica, M-Eslon, M-Oxy, M. O. S., Maalox Anti-Diarrheal, Maldemar, Maolate, maprotiline, Marezine, Marinol, Marplan, MB-TAB, Mebaral, Meclicot, meclizine, Medivert, Mellaril, Mellaril-S, memantine, Meni-D, mepenzolate, meperidine, mephenytoin, mephobarbital, meprobamate, Mesantoin, mesoridazine, metaxalone, methadone, Methadose, methdilazine, methocarbamol, methotrimeprazine, methscopolamine, methsuximide, metoclopramide, midazolam, Milontin, Miltown, Mio-Rel, Miochol, Miochol-E, Miochol-E System Pak, Miochol-E/Steri-Tags, Miostat, Mitran, Moban, molindone, Mono-Vacc Test (O.T.), morphine, morphine 24 hour extended release, morphine extended release, Morphine IR, morphine liposomal, Morphine LP Epidural, morphine preservative-free, Morphine Rapi-Ject, Morphitec, MS, MS Contin, MS/S, MSIR, MSTA Mumps Skin Test Antigen, Multitest CMI, mumps skin test antigen, Myolin, Mysoline, nabilone, nalbuphine, Namenda, Nardil, Nasahist B, Navane, ND-Stat, Nembutal, Nembutal Sodium, Nervine, Neupro, Nightime Sleepaid, Niravam, Nolahist, Norflex, Norflex Injectable, Norpace, Norpace CR, Norpramin, nortriptyline, Nu-Med, Nubain, Nulev, Numorphan HCl, Nytol Caplet, Nytol Maximum Strength, Ocu-Carpine, Ocusert, olanzapine, olopatadine nasal, OMS, Opana, Opana ER, opium, Opium Deodorized, Optimine, Oramorph SR, Orap, Orfro, Ormazine, orphenadrine, orphenadrine extended release, Orphenate, oxazepam, oxcarbazepine, oxybutynin, oxybutynin extended release, oxycodone, oxycodone extended release, OxyContin, Oxyfast, OxyIR, oxymorphone, oxymorphone extended release, Oxytrol, P-Tann, P-Tex, Palgic, paliperidone, Palladone, Palladone SR, Pamelor, Pamine, Pamine Forte, Paradione, Paraflex, Parafon Forte DSC, Paral, paraldehyde, paramethadione, Pardryl, Paregoric, Parlodel, Parnate, Patanase, Paxarel, PBZ, PBZ-SR, PediaTan, Pediatex, Pediatex 12, Pediox, Pediox-S, Peganone, Pentazine, pentazocine, pentobarbital, Pentothal, Pepto Diarrhea Control, Percolone, pergolide, Periactin, Permax, Permitil, perphenazine, phenacemide, Phenadoz, Phenazine 50, phenelzine, Phenergan, Phenergan Fortis, phenindamine, pheniramine, phenobarbital, Phenoject-50, phensuximide, Phenurone, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, Phospholine Iodide, physostigmine, physostigmine ophthalmic, Pilagan with C Cap, Pilocar, pilocarpine nitrate ophthalmic, pilocarpine ophthalmic, Pilopine-HS, Piloptic-1, Piloptic-1/2, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6, Pilostat, pimozide, Polaramine, Polaramine Repetabs, pregabalin, Prialt, primidone, Pristiq, Pro-Banthine, Pro-Med, procainamide, procainamide 12 hour extended release, procainamide extended release, Procan SR, Procanbid, prochlorperazine, prochlorperazine extended release, Procot, procyclidine, Prolixin, Prolixin Decanoate, Prolixin Enanthate, Promacot, promazine, promethazine, Promethegan, Pronestyl, Pronestyl-SR, Prop-A-Tane, propantheline, propiomazine, propofol, Prorex, Prosom, protriptyline, Prozac, Prozac Weekly, Prudoxin, pyrilamine, pyrilamine extended release, Pyrlex, Q-Dryl, Q-Dryl A/F, QDALL AR, Quarzan, quazepam, Quenalin, quetiapine, quetiapine extended release, Quin-G, Quin-Release, Quinaglute Dura-Tabs, Quinidex Extentabs, quinidine, quinidine extended release, Quinora, Rapiflux, Razadyne, Razadyne ER, Reglan, Regurin, Relaxazone, Reminyl, Remular, Remular-S, Rescudose, Restoril, Rezine, Ridramin, Risperdal, Risperdal Consta, Risperdal M-Tab, risperidone, rivastigmine, RMS, Robaxin, Robaxin-750, Robinul, Robinul Forte, Rohist, rotigotine, Roxanol, Roxanol 100, Roxanol-T, Roxicodone, Roxicodone Intensol, Ru-Vert-M, Sal-Tropine, Sanctura, Sanctura XR, Sarafem, Sclavo Test-PPD, Scopace, scopolamine, scopolamine topical, Scot-Tussin Allergy Relief Formula, secobarbital, Seconal Sodium, Selfemra, Serax, Serentil, Seroquel, Seroquel XR, sertraline, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Siltane, Simply Sleep, Sinequan, Skelaxin, Skelex, skin test antigens, multiple, Sleep Tab II, Sleep Tabs, Sleep-ettes, Sleep-Eze-3, Sleepinal, sodium iodide I-123, sodium iodide-I-131, sodium valproate, Solfoton, solifenacin, solotuss, Soma, Sominex, Sominex Maximum Strength Caplet, Somnicaps, Somnote, Sparine, Spasdel, Spherulin, Stadol, Stadol NS, Statex, Stelazine, Strifon Fort, Sublimaze, Subutex, Sufenta, sufentanil, Surmontil, Symax Duotab, Symax FasTab, Symax SL, Symax SR, Symmetrel, Tacaryl, tacrine, Talwin Lactate, Tanacof-XR, TanaHist-PD, Tavist, Tavist Allergy, Tavist-1, Tegretol, Tegretol XR, Temaril, temazepam, tetrahydroaminocrideine, thalidomide, Thalomid, Theraflu Thin Strips Multi Symptom, thiethylperazine, thiopental, thioridazine, thiothixene, Thorazine, Ticon, Tigan, tizanidine, Tofranil, Tofranil-PM, tolterodine, tolterodine extended release, Torecan, Total Allergy, Trancopal, Transderm-Scop, Tranxene SD, Tranxene T-Tab, tranylcypromine, traZODONE, Triaminic Allergy, Triaminic Thin Strips Cough & Runny Nose, triazolam, Trichophyton Allergenic Extracts, trichophyton skin test, Tridione, trifluoperazine, triflupromazine, Trihexane, trihexyphenidyl, Trilafon, Trileptal, trimeprazine, trimethadione, trimethobenzamide, trimipramine, tripelennamine, Tripohist, triprolidine, triprolidine extended release, Triptone, trospium, trospium extended release, Trux-adryl, tuberculin purified protein derivative, Tuberculin Tine Test, Tubersol, Tusstat, Twilite, Uni-Tann, Unisom, Unisom Sleepgels Maximum Strength, Uprima, Urispas, Urotrol, V-Gan-25, V-Gan-50, Valium, valproic acid, Valrelease, Valu-Dryl, Vanadom, Vanatrip, VaZol, Versed, VESIcare, Vistacon, Vistacot, Vistaject-50, Vistaril, Vistaril IM, Vistazine, Vistazine 50, Vivactil, Wal-finate, Xanax, Xanax XR, Xyzal, XYZALL, Zanaflex, Zaponex, Zarontin, Zetran, ziconotide, ziprasidone, Zoloft, zolpidem, zolpidem extended release, Zonalon, Zymine, Zymine XR, Zyprexa, Zyprexa Zydis, Zyrtec, Zyrtec Hives

Minor Interactions
Amphadase, Atrovent, Atrovent HFA, Atrovent Nasal, hyaluronidase, Hydase, Hylenex, ipratropium, ipratropium nasal, Matulane, procarbazine, Spiriva, tiotropium, Vitrase, Wydase

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