Drug interactions between Dilantin and Kaopectate
Results for the following 2 drugs: |
|
|---|---|
| Dilantin (phenytoin) | |
| Kaopectate (bismuth subsalicylate) | |
Interactions between your selected drugs
phenytoin ⇔ bismuth subsalicylate
Applies to: Dilantin (phenytoin) and Kaopectate (bismuth subsalicylate)
In vitro studies suggest that salicylates may displace phenytoin from plasma protein-binding sites. The potential for phenytoin toxicity exists. The clinical significance is unknown. One case of phenytoin toxicity has been reported in a patient taking aspirin. However, clinical studies in healthy subjects and epileptic patients (taking phenytoin and 1500 mg aspirin/day) have not reported significant pharmacokinetic changes, adverse effects, or loss of seizure control.
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