Drug interactions between Digitek and omeprazole
Results for the following 2 drugs: |
|
|---|---|
| Digitek (digoxin) | |
| omeprazole | |
Interactions between your selected drugs
digoxin ⇔ omeprazole
Applies to: Digitek (digoxin) and omeprazole
Proton pump inhibitors may increase the bioavailability of digoxin. The proposed mechanism is a pH-dependent increase in gastrointestinal absorption of digoxin. The clinical significance of this effect is unknown. In patients treated with proton pump inhibitors, the possibility of an enhanced pharmacologic response to digoxin should be considered. Patients should be closely monitored for development of toxicity, particularly those with digoxin levels in the upper range of normal. Patients should be advised to notify their physician if they experience nausea, anorexia, visual changes, slow pulse, or irregular heartbeats.
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