Interactions between desloratadine and Hylenex (hyaluronidase)
hyaluronidase and desloratadine (Minor Drug-Drug)
Larger amounts of hyaluronidase may be required to achieve equivalent dispersing effects if patients are concomitantly receiving large doses of salicylates, cortisone, ACTH, estrogens, or antihistamines. These drugs may render tissues partially resistant to the dispersing action of hyaluronidase.