Drug interactions between Depakene and Prozac
Results for the following 2 drugs: |
|
|---|---|
| Depakene (valproic acid) | |
| Prozac (fluoxetine) | |
Interactions between your selected drugs
valproic acid ⇔ fluoxetine
Applies to: Depakene (valproic acid) and Prozac (fluoxetine)
Individual case reports suggest that fluoxetine may increase valproate levels, perhaps by inhibiting the hepatic metabolism of valproate. Another study of two patients suggests that valproate may enhance the therapeutic effects of fluoxetine. The mechanism is unknown. Patients should be monitored for altered pharmacologic effects and increased valproic acid levels if these drugs are administered concomitantly.
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