Drug interactions between Depakene and Motrin
Results for the following 2 drugs: |
|
|---|---|
| Depakene (valproic acid) | |
| Motrin (ibuprofen) | |
Interactions between your selected drugs
ibuprofen ⇔ valproic acid
Applies to: Motrin (ibuprofen) and Depakene (valproic acid)
High doses of ibuprofen (greater than 400 mg/day) may displace valproic acid from protein binding sites in vitro. This interaction may be more significant in uremic patients. Free valproic acid concentrations should be measured if toxicity is suspected.
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