Drug interactions between danazol and Viagra
Results for the following 2 drugs: |
|
|---|---|
| danazol | |
| Viagra (sildenafil) | |
Interactions between your selected drugs
danazol ⇔ sildenafil
Applies to: danazol and Viagra (sildenafil)
MONITOR: Coadministration with inhibitors of CYP450 3A4 may increase the plasma concentrations of sildenafil, which is primarily metabolized by the isoenzyme. The possibility of prolonged and/or increased pharmacologic effects of sildenafil should be considered.
MANAGEMENT: Caution is advised if sildenafil is coadministered with CYP450 3A4 inhibitors. Dosage adjustments may be appropriate for sildenafil whenever a CYP450 3A4 inhibitor is added to or withdrawn from therapy based on efficacy and side effects. Patients should be advised to promptly notify their physician if they experience pain or tightness in the chest or jaw, irregular heartbeat, nausea, shortness of breath, visual disturbances, syncope, or prolonged erection (greater than 4 hours).
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