Drug interactions between Coumadin and timolol
Results for the following 2 drugs: |
|
|---|---|
| Coumadin (warfarin) | |
| timolol | |
Interactions between your selected drugs
warfarin ⇔ timolol
Applies to: Coumadin (warfarin) and timolol
Some oral beta-blockers may increase serum levels of oral anticoagulants and enhance anticoagulant effects. The mechanism is unknown . Data have been conflicting. Case reports exist for propranolol, while acebutolol, atenolol, betaxolol, bisoprolol, carvedilol, esmolol, metoprolol, and pindolol reportedly do not interact. Hypoprothrombinemic effects are expected to be minimal. It is recommended that PT or INR be monitored when a beta-blocker is added to or deleted from the medical regimen of a patient receiving an oral anticoagulant. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
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