Drug Interactions

Drug interactions between Coumadin and spironolactone

Results for the following 2 drugs:

Coumadin (warfarin)
spironolactone

Interactions between your selected drugs

warfarin ⇔ spironolactone

Applies to: Coumadin (warfarin) and spironolactone

Spironolactone may cause diuresis and hemoconcentration of clotting factors. The effects of some anticoagulants may be decreased. Data are available for warfarin. The INR or PT should be monitored, and oral coagulant dosage should be increased as needed.

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