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Drug Interactions between Cotabflu and Lomocot

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

codeine atropine

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine) and Lomocot (atropine / diphenoxylate)

Using codeine together with atropine may increase the risk and/or severity of some side effects such as dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

codeine chlorpheniramine

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine) and Cotabflu (acetaminophen / chlorpheniramine / codeine)

Using codeine together with chlorpheniramine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

atropine chlorpheniramine

Applies to: Lomocot (atropine / diphenoxylate) and Cotabflu (acetaminophen / chlorpheniramine / codeine)

Using atropine together with chlorpheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems. Side effects may be more likely to occur in the elderly or those with a debilitating condition. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

codeine diphenoxylate

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine) and Lomocot (atropine / diphenoxylate)

Using diphenoxylate together with codeine can increase the blood levels or add to the side effects of either medication. Talk with your doctor before using these medications together. Call the doctor if you have side effects such as extreme drowsiness, dizziness, weak pulse, slow heart rate, sweating, urinating less than usual, severe stomach cramps or bloating, and vomiting. You should avoid activities requiring mental alertness until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chlorpheniramine diphenoxylate

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine) and Lomocot (atropine / diphenoxylate)

Using chlorpheniramine together with diphenoxylate may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

acetaminophen atropine

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine) and Lomocot (atropine / diphenoxylate)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Major

acetaminophen food

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine)

Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

chlorpheniramine food

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine)

Alcohol can increase the nervous system side effects of chlorpheniramine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with chlorpheniramine. Do not use more than the recommended dose of chlorpheniramine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

diphenoxylate food

Applies to: Lomocot (atropine / diphenoxylate)

Alcohol can increase the nervous system side effects of diphenoxylate such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with diphenoxylate. Do not use more than the recommended dose of diphenoxylate, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Moderate

codeine food

Applies to: Cotabflu (acetaminophen / chlorpheniramine / codeine)

Do not use alcohol or medications that contain alcohol while you are receiving treatment with codeine. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. With certain long-acting formulations of narcotic pain medication, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of codeine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

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Moderate

atropine food

Applies to: Lomocot (atropine / diphenoxylate)

Ask your doctor before using atropine together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking atropine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.